{"id":9850,"date":"2024-09-27T20:12:05","date_gmt":"2024-09-27T17:12:05","guid":{"rendered":"https:\/\/kirsehirsondakika.com.tr\/?p=9850"},"modified":"2024-09-27T20:12:05","modified_gmt":"2024-09-27T17:12:05","slug":"genc-yasta-baslayan-alzheimer-daha-agresif-olabilir-fiziksel-aktivite-ve-diyet-secimleri-genc-yasta-alzheimer-riskini-dusurebilir","status":"publish","type":"post","link":"https:\/\/kirsehirsondakika.com.tr\/index.php\/2024\/09\/27\/genc-yasta-baslayan-alzheimer-daha-agresif-olabilir-fiziksel-aktivite-ve-diyet-secimleri-genc-yasta-alzheimer-riskini-dusurebilir\/","title":{"rendered":"Gen\u00e7 ya\u015fta ba\u015flayan Alzheimer daha agresif olabilir! Fiziksel aktivite ve diyet se\u00e7imleri gen\u00e7 ya\u015fta Alzheimer riskini d\u00fc\u015f\u00fcrebilir!"},"content":{"rendered":"

Baz\u0131 nadir vakalarda 30\u2019lu ya\u015flarda belirtilerin g\u00f6r\u00fclebildi\u011fine dikkat \u00e7eken N\u00f6roloji Uzman Prof. Dr. Sultan Tarlac\u0131, \u201cTan\u0131 an\u0131nda daha az bili\u015fsel bozuklu\u011fa sahip olsalar da, \u00e7al\u0131\u015fmalar gen\u00e7 ba\u015flang\u0131\u00e7l\u0131 Alzheimer hastal\u0131\u011f\u0131yla ya\u015fayanlar\u0131n beyinlerinde daha h\u0131zl\u0131 de\u011fi\u015fiklikler oldu\u011funu g\u00f6stermi\u015ftir. Bu, durumun ge\u00e7 ba\u015flang\u0131\u00e7l\u0131 Alzheimer hastal\u0131\u011f\u0131ndan daha agresif olabilece\u011fini g\u00f6sterir.\u201d dedi. Prof. Dr. Sultan Tarlac\u0131 ayr\u0131ca baz\u0131 ara\u015ft\u0131rmalara g\u00f6re, genetik olarak Alzheimer riski alt\u0131nda olanlar\u0131n daha aktif olarak ve beslenme \u015fekline dikkat ederek gen\u00e7 ya\u015fta Alzheimer hastal\u0131\u011f\u0131na yakalanma riskini d\u00fc\u015f\u00fcrebileceklerine vurgu yapt\u0131.<\/strong><\/p>\n

\u00dcsk\u00fcdar \u00dcniversitesi NP\u0130STANBUL Hastanesi N\u00f6roloji Uzman Prof. Dr. Sultan Tarlac\u0131, gen\u00e7 ya\u015fta ba\u015flayan Alzheimer hakk\u0131nda bilgi verdi.<\/p>\n

Dikkat azl\u0131\u011f\u0131 ve mek\u00e2nsal fark\u0131ndal\u0131kta azalma gen\u00e7 ya\u015fta ba\u015flayan Alzheimer\u2019\u0131n ilk belirtileri olabilir!<\/strong><\/p>\n

Gen\u00e7 ya\u015fta ba\u015flayan Alzheimer hastal\u0131\u011f\u0131 hakk\u0131nda bilgi birikimi artm\u0131\u015f olsa da, bu hastal\u0131\u011f\u0131n alt\u0131nda yatan mekanizmalar hakk\u0131nda h\u00e2l\u00e2 bir\u00e7ok soru oldu\u011funa i\u015faret eden Prof. Dr. Sultan Tarlac\u0131, \u201cGen\u00e7 ya\u015fta Alzheimer hastal\u0131\u011f\u0131, genellikle 65 ya\u015f\u0131ndan \u00f6nce ba\u015flayan ve genetik fakt\u00f6rlerin rol oynad\u0131\u011f\u0131 bir Alzheimer hastal\u0131\u011f\u0131 formudur. Bu hastal\u0131k, Alzheimer’\u0131n klasik belirtilerine erken ya\u015fta yol a\u00e7ar ve genellikle daha h\u0131zl\u0131 ilerler.\u201d dedi.<\/p>\n

Takip ettikleri Alzheimer hastalar\u0131 aras\u0131nda \u015fu anda 44 ya\u015f\u0131nda bir kad\u0131n hasta oldu\u011funu dile getiren Prof. Dr. Sultan Tarlac\u0131, \u015funlar\u0131 s\u00f6yledi:<\/p>\n

\u201c40 ya\u015flar\u0131nda ba\u015flam\u0131\u015f ve olduk\u00e7a y\u0131k\u0131c\u0131 bir duruma gelmi\u015f. \u00d6ncelikle belirtiler \u00e7ok daha erken ba\u015flayabilir. Baz\u0131 nadir vakalarda 30 kadar erken ya\u015flarda bile g\u00f6r\u00fclebilir, ancak genellikle 50-64 ya\u015flar\u0131 aras\u0131nda te\u015fhis edilir. Alzheimer hastal\u0131\u011f\u0131 olan ki\u015filerde hastal\u0131\u011f\u0131n ilk belirtisi olarak haf\u0131za kayb\u0131 s\u0131kl\u0131kla g\u00f6r\u00fcl\u00fcrken, gen\u00e7 ya\u015fta ba\u015flayan Alzheimer hastal\u0131\u011f\u0131 olan ki\u015filerde daha az dikkat, el hareketlerini taklit etme becerisinde azalma ve mek\u00e2nsal fark\u0131ndal\u0131kta azalma gibi ba\u015fka belirtiler de g\u00f6r\u00fclme e\u011filimi vard\u0131r. Ara\u015ft\u0131rmalar, duyusal ve hareketle ilgili bilgileri i\u015flemekle g\u00f6revli beyin b\u00f6lgelerinin (parietal korteks olarak adland\u0131r\u0131l\u0131r) daha fazla hasar belirtisi g\u00f6sterdi\u011fini bulmu\u015ftur. Ayr\u0131ca, \u00f6\u011frenme ve haf\u0131zada \u00f6nemli bir beyin b\u00f6lgesi olan hipokamp\u00fcste ge\u00e7 ba\u015flang\u0131\u00e7l\u0131 Alzheimer’a k\u0131yasla daha az hasar vard\u0131r.\u201d<\/p>\n

Gen\u00e7 ba\u015flang\u0131\u00e7l\u0131 Alzheimer hastalar\u0131n\u0131n beyinlerinde daha h\u0131zl\u0131 de\u011fi\u015fiklikler oluyor\u2026\u00a0<\/strong><\/p>\n

\u201cTan\u0131 an\u0131nda daha az bili\u015fsel bozuklu\u011fa sahip olsalar da, \u00e7al\u0131\u015fmalar gen\u00e7 ba\u015flang\u0131\u00e7l\u0131 Alzheimer hastal\u0131\u011f\u0131yla ya\u015fayanlar\u0131n beyinlerinde daha h\u0131zl\u0131 de\u011fi\u015fiklikler oldu\u011funu g\u00f6stermi\u015ftir.\u201d diyen Prof. Dr. Sultan Tarlac\u0131, \u201cBu, durumun ge\u00e7 ba\u015flang\u0131\u00e7l\u0131 Alzheimer hastal\u0131\u011f\u0131ndan daha agresif olabilece\u011fini g\u00f6sterir. Ayr\u0131ca erken ba\u015flang\u0131\u00e7l\u0131 Alzheimer hastal\u0131\u011f\u0131 olan ki\u015filerin ge\u00e7 ba\u015flang\u0131\u00e7l\u0131 olanlara g\u00f6re yakla\u015f\u0131k iki y\u0131l daha k\u0131sa bir ya\u015fam beklentisine sahip olmalar\u0131n\u0131n nedenini de a\u00e7\u0131klayabilir.\u201d \u015feklinde konu\u015ftu.<\/p>\n

Daha sa\u011fl\u0131kl\u0131 bir ya\u015fam tarz\u0131yla hastal\u0131\u011fa kar\u015f\u0131 dayan\u0131kl\u0131l\u0131k g\u00fc\u00e7lendirilebilir\u2026<\/strong><\/p>\n

Demans aile ge\u00e7mi\u015fi olan veya riskleri konusunda endi\u015fe duyan ki\u015filere genetik test yapt\u0131rabilece\u011fine de\u011finen Prof. Dr. Sultan Tarlac\u0131, \u201cBu, hatal\u0131 genlerin varl\u0131\u011f\u0131n\u0131 do\u011frulayacakt\u0131r. Bu testler, semptomlar g\u00f6sterenler veya gelecekteki prognozlar\u0131n\u0131 bilmek isteyenler i\u00e7in yap\u0131labilir.\u201d dedi.<\/p>\n

Baz\u0131 ara\u015ft\u0131rmalar\u0131n, daha fazla risk alt\u0131nda olan ki\u015filerin, geneti\u011fi de\u011fi\u015ftirmek m\u00fcmk\u00fcn olmasa da, daha sa\u011fl\u0131kl\u0131 bir ya\u015fam tarz\u0131yla hastal\u0131\u011fa kar\u015f\u0131 dayan\u0131kl\u0131l\u0131\u011f\u0131n\u0131 g\u00fc\u00e7lendirebilece\u011fi fikrini destekledi\u011fine dikkat \u00e7eken Prof. Dr. Sultan Tarlac\u0131, \u015funlar\u0131 s\u00f6yledi:<\/p>\n

\u201cBir \u00e7al\u0131\u015fma , genetik olarak erken ba\u015flang\u0131\u00e7l\u0131 Alzheimer’a yatk\u0131n olan ki\u015filerin haftada iki bu\u00e7uk saatten fazla egzersiz yapt\u0131klar\u0131nda, fiziksel olarak daha az aktif olanlara g\u00f6re haf\u0131za testlerinde daha iyi puan ald\u0131klar\u0131n\u0131 buldu. Daha aktif olman\u0131n yan\u0131 s\u0131ra, diyet se\u00e7imleri gen\u00e7 ya\u015fta Alzheimer riskini de d\u00fc\u015f\u00fcrebilir. Y\u00fcksek d\u00fczeyde sebze, kuru meyve ve \u00e7ikolata t\u00fcketen ki\u015filer daha d\u00fc\u015f\u00fck riske sahiptir. Gen\u00e7 demanslarda depresyon s\u0131kt\u0131r ve tedavi edilmelidir.\u00a0<\/p>\n

Bili\u015fsel rehabilitasyon programlar\u0131, hastalar\u0131n bellek ve di\u011fer bili\u015fsel i\u015flevlerini g\u00fc\u00e7lendirmeyi hedefler. Bu programlar genellikle \u00f6zel egzersizler ve stratejiler i\u00e7erir. Hastalar ve aile \u00fcyeleri i\u00e7in destek gruplar\u0131, psikolojik dan\u0131\u015fmanl\u0131k ve e\u011fitim programlar\u0131, hastal\u0131\u011f\u0131n duygusal ve sosyal y\u00f6nleriyle ba\u015fa \u00e7\u0131kmalar\u0131na yard\u0131mc\u0131 olabilir. D\u00fczenli fiziksel egzersiz, genel sa\u011fl\u0131k durumunu iyile\u015ftirebilir ve bili\u015fsel fonksiyonlar\u0131 destekleyebilir. Ayr\u0131ca, egzersiz sosyal etkile\u015fimi te\u015fvik edebilir. \u0130la\u00e7lar tek ba\u015f\u0131na, haf\u0131za ve bili\u015fsel i\u015flevlerin korunmas\u0131na yard\u0131mc\u0131 olabilir, ancak genellikle hastal\u0131\u011f\u0131n ilerlemesini durdurmazlar. Etkileri ki\u015fiden ki\u015fiye de\u011fi\u015febilir.\u201d<\/p>\n

On vakadan birinin sorumlusu genetik\u2026\u00a0<\/strong><\/p>\n

Gen\u00e7 ya\u015fta ortaya \u00e7\u0131kan Alzheimer hastal\u0131\u011f\u0131n\u0131n risk fakt\u00f6rleri ile ge\u00e7 ya\u015fta ortaya \u00e7\u0131kan Alzheimer hastal\u0131\u011f\u0131n\u0131n risk fakt\u00f6rlerinin benzer oldu\u011funun alt\u0131n\u0131 \u00e7izen Prof. Dr. Sultan Tarlac\u0131, s\u00f6zlerini \u015f\u00f6yle tamamlad\u0131:<\/p>\n

\u201cGen\u00e7 ba\u015flang\u0131\u00e7l\u0131 Alzheimer hastal\u0131\u011f\u0131n\u0131n yakla\u015f\u0131k on vakas\u0131ndan birinde geneti\u011fin rol oynad\u0131\u011f\u0131 biliniyor. \u015eimdiye kadar, \u00fc\u00e7 gen ( APP, PSEN1 ve PSEN2 ) gen\u00e7 ba\u015flang\u0131\u00e7l\u0131 Alzheimer hastal\u0131\u011f\u0131yla ili\u015fkilendirilmi\u015ftir. Gen\u00e7 Alzheimer hastalar\u0131n\u0131n genetik \u00f6zellikleri ve hastal\u0131\u011f\u0131n biyolojik mekanizmalar\u0131 \u00fczerine yap\u0131lan ara\u015ft\u0131rmalar, tedavi stratejilerinin ki\u015fiselle\u015ftirilmesine ve hedeflenmesine olanak tan\u0131yabilir. \u00d6zellikle genetik mutasyonlar\u0131 hedefleyen tedavi y\u00f6ntemleri geli\u015ftirilmesine katk\u0131da bulunabilir. Gen\u00e7 ya\u015fta Alzheimer hastal\u0131\u011f\u0131n\u0131n patofizyolojik mekanizmalar\u0131n\u0131 anlamak, Alzheimer hastal\u0131\u011f\u0131n\u0131n genel patofizyolojisini daha iyi kavrayabilmemizi sa\u011flar. Bu bilgi, hastal\u0131\u011f\u0131n erken d\u00f6nemlerini, ilerleyi\u015fini ve nas\u0131l \u00f6nlenebilece\u011fini anlamak i\u00e7in \u00f6nemli olabilir.\u201d<\/p>\n

Kaynak: (BYZHA) Beyaz Haber Ajans\u0131<\/p>\n","protected":false},"excerpt":{"rendered":"

Gen\u00e7 ya\u015fta ba\u015flayan Alzheimer hastal\u0131\u011f\u0131n\u0131, genellikle 65 ya\u015f\u0131ndan \u00f6nce ba\u015flayan ve genetik fakt\u00f6rlerin rol oynad\u0131\u011f\u0131 bir Alzheimer hastal\u0131\u011f\u0131 formu olarak tan\u0131mlayan uzmanlar, gen\u00e7 ya\u015fta ba\u015flayan hastal\u0131\u011f\u0131n, Alzheimer\u2019\u0131n klasik belirtilerinin erken ya\u015fta g\u00f6r\u00fclmesine ve daha h\u0131zl\u0131 ilerlemesine neden oldu\u011funu s\u00f6yl\u00fcyor.<\/p>\n","protected":false},"author":1,"featured_media":9851,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[3455,2028,717,1500,3456],"class_list":["post-9850","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-saglik","tag-alzheimer-hastaligi","tag-gen","tag-hasta","tag-hastaligi","tag-prof-dr-sultan-tarlaci"],"_links":{"self":[{"href":"https:\/\/kirsehirsondakika.com.tr\/index.php\/wp-json\/wp\/v2\/posts\/9850"}],"collection":[{"href":"https:\/\/kirsehirsondakika.com.tr\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/kirsehirsondakika.com.tr\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/kirsehirsondakika.com.tr\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/kirsehirsondakika.com.tr\/index.php\/wp-json\/wp\/v2\/comments?post=9850"}],"version-history":[{"count":1,"href":"https:\/\/kirsehirsondakika.com.tr\/index.php\/wp-json\/wp\/v2\/posts\/9850\/revisions"}],"predecessor-version":[{"id":9852,"href":"https:\/\/kirsehirsondakika.com.tr\/index.php\/wp-json\/wp\/v2\/posts\/9850\/revisions\/9852"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/kirsehirsondakika.com.tr\/index.php\/wp-json\/wp\/v2\/media\/9851"}],"wp:attachment":[{"href":"https:\/\/kirsehirsondakika.com.tr\/index.php\/wp-json\/wp\/v2\/media?parent=9850"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/kirsehirsondakika.com.tr\/index.php\/wp-json\/wp\/v2\/categories?post=9850"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/kirsehirsondakika.com.tr\/index.php\/wp-json\/wp\/v2\/tags?post=9850"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}